A novel synthetic derivative of biaryl guanidine as a potential BACE1 inhibitor, to treat Alzheimer’s disease: In-silico, in-vitro and in-vivo evaluation Page No: 1339-1345

By: Sayyad Ali, Muhammad Hassham Hassan Bin Asad, Muhammad Arslan Javed, Tariq Javed, Yasser MSA Al-Kharaman, Muhammad Latif, Sabeeh Mohsin, Taufiq Nawaz, Syed Muhammad Farid Hasan, Jamshed Iqbal, Borhan Babak, Izhar Hussain

Keywords: Biaryl guanidine, Alzheimer’s disease, BACE1, inhibition

DOI : 10.36721/PJPS.2022.35.5.REG.1339-1345.1

Abstract: BACE1 enzyme has been known a potential target involved in Alzheimer’s disease (AD). Present research was focused on the principles of virtually screening



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