Fabrication of ticagrelor bioadhesive solid dispersion based on coaxial electrostatic spray to improve drug release and enhance oral bioavailability Page No: 121-127

By: Hongfei Liu, Hui Zhang, Chunguang Gu, Xiaoyan Chen, Yingshu Feng, Caleb Kesse Firempong, Haibing He, Changshan Sun

Keywords: Ticagrelor; uniaxial electrostatic spray; coaxial electrostatic spray; solid dispersion; bioadhesion

DOI : 10.36721/PJPS.2023.36.1.REG.121-127.1

Abstract: Due to the low solubility and poor bioavailability of Ticagrelor (TIC), the current study developed a structured bioadhesive core-shell drug delivery system



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