Formulation, in-vitro evaluation and optimization of valsartan nano-lipid complex by Box-Behnken design Page No: 1249-1260

By: Magdy I Mohamed, Hanaa A Mahmoud, Amir I Mohamed, Nesrin M Nabil, Mohamed A Kasssem, Yousef A Elsherif

Keywords: Valsartan, complexsomes, phospholipid, box-behnken design

DOI : 10.36721/PJPS.2023.36.4.REG.1249-1260.1

Abstract: The antihypertensive drug valsartan, has an imperfect bioavailability due to its low solubility, permeability and excessive first pass hepatic metabolism



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