Novel pyrimidine derivatives and black cumin as xanthine oxidase inhibitors: synthesis, docking study and formulation
Page No: 00
By: Salam Waheed Ahjel, Suhad Sami Humadi, Samir Mohamed Awad, Mohamed Fathy El-Shehry, Yara Essam Mansour, Ahmed Abd elkader El-Rashedy
Keywords: Black seed, pyrimidine and triazolopyrimidines, xanthine oxidase inhibitors, effervescent granules, Docking Study.
DOI : 10.36721/PJPS.0000.00.0.REG.000-000.1
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By: Salam Waheed Ahjel, Suhad Sami Humadi, Samir Mohamed Awad, Mohamed Fathy El-Shehry, Yara Essam Mansour, Ahmed Abd elkader El-Rashedy
Keywords: Black seed, pyrimidine and triazolopyrimidines, xanthine oxidase inhibitors, effervescent granules, Docking Study.
DOI : 10.36721/PJPS.0000.00.0.REG.000-000.1
Abstract: The enzyme xanthine oxidase is crucial to the development of hyperuricemia and gout owing to the fact that it acts as a catalyst for the oxidation reaction that turns hypoxanthine and xanthine into uric acid
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