By: Ying Guo, Jianzhou Ye
Keywords: Atopic dermatitis; Modified Qingxin Decoction for Invigorating the striking; Itching degree; Clinical effect; security
DOI : 10.36721/PJPS.2025.38.2.REG.13757.1
Abstract: We aimed to explore the Modified Qingxin Decoction for Invigorating the Spleen (MQDIS) in the treatment of atopic dermatitis (AD) the efficacy and safety. We selected AD192 patients treated from June 2018 to June 2023 as a retrospective case-control study, and divided the patients into the observation group and the comparison group with 96 cases. Patients in the control group received conventional treatment. Observation group was treated with MQDIS on the basis of comparison group. Symptoms and signs, Scoring Atopic Dermatitis Index (SCORAD) score, itch score, dryness score and quality of life index were analyzed in the two groups. The improvement of skin area, severity, pruritus and sleep in the comparison group was better than that in the observation group, especially in the severity and sleep, and the statistical difference was very significant.(P-value<0.05).SCORAD score and itch degree of both groups decreased, the difference was statistically significant.(P-value<0.05).MQDIS for treating AD had a good effect on improving various points of skin lesion, dry points and quality of life, and the recurrence rate was lower, it was safe and effective.
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