In vitro dissolution and physicochemical characterizations of novel PVP-based solid dispersions containing valsartan prepared by a freeze-drying method Page No: 1799-1804

By: Wei-Juan Xu, Yan Liu, Li-Li Shi, Jing-Hao Cui, Qing-Ri Cao

Keywords: Valsartan, solid dispersion, freeze-drying, dissolution, physicochemical property.

Abstract: Valsartan (VAL) shows poor oral bioavailability mainly as a result of its low water solubility at low pH



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