In vitro antimalarial and xanthine oxidase inhibition of 2-Aminoanthraquinone Page No: 429-432

By: Abdur Rauf, Rehan Khan, Haroon Khan, Noor Jehan, Mohammad Akram, Zarka Ahmad, Naveed Muhammad, Umar Farooq, Ajmal Khan

Keywords: 2-Aminoanthraquinone, anti-malarial and xanthine oxidase.

Abstract: In the present research study 2-Aminoanthraquinone were scrutinized for their antimalarial and Xanthine oxidase inhibitor potential. It demonstrated marked concentration dependent antimalarial activity with maximum effect of 89.06% and with IC50 of 34.17 µM. Regarding Xanthine oxidase inhibitor activity, it evoked significant effect with 57.45% activity with IC50 value of 81.57.19µM. In conclusion, 2-Aminoanthraquinone showed potent antimalarial and xanthine oxidase inhibitory activity.



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