Complexation of ibuprofen with water soluble p-sulfonatocalix [4]arene: A potential candidate for drug delivery application Page No: 783-788

By: Tahira S. Khokhar, Shahabuddin Memon, Qadeer K. Panhwar, Fakhar N Memon, Ayaz A. Memon, Muhammad Qasim Samejo, Saba Muneer, Metin Tulu

Keywords: Synthesis, inclusion complex, p-sulfonatocalix[4]arene, thermodynamic, drug delivery.

Abstract: Complexation of ibuprofen with water soluble p-sulfonatocalix[4]arene (3) was evaluated. Both molecules exhibit a host and guest type complexation. pH, complex stoichiometry and binding constant were determined by UV-Vis and FT-IR spectroscopy



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