Evaluation of ED50 and 5?-reductase inhibitor activities of some thiopyrimidine, pyrane, pyrazoline, and thiazolopyrimidine derivatives Page No: 833-838

By: Abd El-Galil E. Amr, Mohamed A. Al-Omar, Mohamed M Abdalla

Keywords: Citrazinic acid, pyrimidinone, thiazolopyrimidine, anstrazole, 5?-reductase inhibitors.

Abstract: In this work, twenty-one thiopyrimidine (1-21) candidates containing a pyrane, pyrazoline and thiazolopyrimidine ring screened for their ED50 and 5a-reductase inhibitors comparable to that of Anastrozole as positive drug.



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