Preparation, characterization and in vivo evaluation of pharmacological activity of different crystal forms of ibuprofen Page No: 2139-2147

By: Yanxiang Li, Feng Yao, Chenxu Shang, Feng Ren, Jiye Zhang, Yanan Li, Guangde Yang, Rong Lin, Weirong Wang

Keywords: Crystal habit, dissolution test, antinociceptive activity, anti-inflammatory activity, ibuprofen.

Abstract: Different polymorphic forms can affect the performance of the drug product. In addition, isomorphic crystals show different chemical and physical properties due to the changes in the crystal habit.



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