Blood pressure lowering effect of selected pyrimidine derivatives mediated through inhibition of calcium channel: A computational approach Page No: 1513-1522

By: Nadeem Irshad, Arif-ullah Khan, Yousaf Kamal, Muhammad Nasir Iqbal

Keywords: Pyrimidines, computational pharmacology, docking, simulation

DOI : 10.36721/PJPS.2022.35.6.REG.1513-1522.1

Abstract: Pyrimidine 2, 4, 6-trione derivatives are known to have L-type calcium channel blockade activity due to which they are quite effective in cardiovascular diseases along with cancer, epilepsy and inflammatory disorders



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