Optimization of ranitidine hydrochloride based on stability performance in directly compressible immediate and sustained release formulations Page No: 525-533

By: Ali Aun, Sana Hanif, Ijaz Ali, Sobia Razzaq, Ejaz Basheer, Rushda Bedar, Tayyaba Aftab, Misha Irshad, Taqi Muhammad, Osama Anwar, Hafiz Abdul Rehman, Alina Mazhar, Muhammad Ali Syed

Keywords: Ranitidine HCl, stability, starch 1500, sustain release, ICH guidelines, avicel® PH102, stability studies

DOI : 10.36721/PJPS. 2023.36.2.REG.525-533.1

Abstract: Ranitidine hydrochloride (RTD), a moisture-sensitive drug, has issues of stability during shelf life especially when formulated through wet granulation method



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